Gamma Glutamyl


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It may be ordered when someone has an elevated Alkaline phosphatase level or as a part of a liver panel to screen for liver damage. It may be ordered as a follow up to other liver function tests when a person has signs and symptoms like jaundice, loss of appetite, abdominal pain, itching, dark urine. Gamma-glutamyl transferase (GGT) is an enzyme found in many organs throughout the body, with the liver having the highest concentration. GGT levels in the blood get elevated in most disorders that affect the liver or bile ducts. This test determines the amount of GGT present in a blood sample. GGT is present in small amounts in the blood, but when the liver is damaged, the level of GGT increases. When the bile ducts become clogged due to tumors or stones, GGT is the first liver enzyme to rise in the blood. GGT is a sensitive enzyme test used for the diagnosis of bile duct issues. It increases with many types of liver disorders, such as liver cancer and viral hepatitis. Gamma GT test chart spikes up in non-hepatic ailments, such as Acute Coronary Syndrome. Due to these reasons, the GGT test does not help in differentiating between various causes of liver damage. As a result, the GGT test is not a routine test. The gamma GT test is used for the diagnosis of causes obstructing the bile duct and for monitoring liver functioning. It is used in conjunction with other tests to determine the source of a high level of alkaline phosphatase (ALP), another liver enzyme. In liver diseases, GGT and ALP show an increase. The ALP is also increased in bone disorders. As a result, GGT is helpful as a follow-up test to establish whether an elevated ALP result is related to liver or bone illness. The gamma GT test results help determine why the alkaline phosphatase (ALP) is high. In bile duct illness and several liver diseases, ALP and GGT show elevation, while only ALP is elevated in bone diseases. As a result, if a person’s gamma GT values are in the normal range but their ALP is high, the cause is most likely a bone disease. The gamma GT test reports help in detecting liver disease and bile duct obstructions. GGT tests are ordered along with other liver tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), ALP and Gamma-glutamyl transpeptidase. An increased gamma GT value indicates liver damage but does not reveal the condition that is causing it.


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